Where to Stay in Panama City

Casco Viejo is Panama City's historic heart and a UNESCO World Heritage site, featuring charming cobblestone streets lined with colorful colonial buildings, boutique hotels, and trendy rooftop bars. Once a neglected area, it has transformed into the city's most desirable neighborhood for tourists and digital nomads seeking atmosphere and character. The walkable streets offer art galleries, museums, the Panama Canal Museum, and the stunning Metropolitan Cathedral. Nightlife is vibrant with options like Tantalo rooftop bar. However, expect tourist crowds, some noise at night, and higher prices. Adjacent areas like El Chorrillo should be avoided after dark.

El Cangrejo is Panama City's bohemian international district with a significant expat population and authentic local character. The neighborhood offers excellent public transportation connections including metro access, making commuting easy. Via Argentina is the main artery, lined with cafes, bars, restaurants, and shops catering to a young, creative crowd. The area has a more lived-in feel compared to glossy Punta Pacifica, with mid-range housing options and a genuine neighborhood vibe. Digital nomads appreciate the abundance of laptop-friendly cafes like Mentiritas Blancas and the proximity to Parque Andres Bello for green space. Less touristy but very welcoming to foreigners.

Obarrio is Panama City's financial district and a dynamic neighborhood combining residential comfort with commercial convenience. Streets are lined with embassies, upscale shops, restaurants, casinos, and hotels including the Sortis Hotel with its delightful rooftop pool. The area is safe day and night with guards at most buildings. High-rise apartments offer great options for short and long-term rentals, though prices are higher than elsewhere. Several coworking spaces including Panama Coworking Center and Workings are within walking distance. The neighborhood suits professionals who want modern amenities and a sense of security.

Punta Pacifica is Panama City's most exclusive waterfront neighborhood, featuring luxury high-rises with stunning Pacific Ocean views. The area is home to Multiplaza Mall for upscale shopping and the Johns Hopkins-affiliated Hospital Punta Pacifica providing world-class healthcare. Modern apartments come with premium amenities like pools, gyms, and 24-hour security. The neighborhood attracts wealthy Panamanians and expatriates seeking tranquility without sacrificing city conveniences. Workings Latam coworking operates from Torre de Las Americas here. The trade-off is higher costs and a somewhat sterile atmosphere compared to characterful areas like Casco Viejo.